Don't give up on taurine. Like everything else it may need to reach a level of homeostasis. It may also contribute to the salt pool in the inner ear. Here are some links for taurine. One is an AI. through Brave. AI's are useful, but biased by the developer. Any need for more information, ask. Seem if there is some blocking going on. I saw this with groups before. If you don't get the links. Let me know. Larry
Hello Mountain Man. To date, there is no good test for histamine intolerance; just measuring levels in the blood is apparently a test that is not an accepted method. Please refer to this National Library of Medicine article on the subject of Histamine Intolerance and in particular section 4 which discusses tests that are more commonly used but the issues with each (and why just going with your own trial and error method may still be the best): Histamine Intolerance: Symptoms, Diagnosis, and Beyond - PMC
Hi Rubygirl Thank you for the link. I can now hear a little better again. I don't yet know whether this is a normal fluctuation or has to do with the reduction in histamine. How long did it take for you to hear normally again?
Hello again Mountain Man! Thankfully while my hearing would noticeably decline when I was having an attack of vertigo, in general I have not lost my hearing in my "Meniere's ear". Perhaps because I was able to turn things around and minimize/prevent attacks reasonably early on before any permanent damage was done. While I cannot say how long it may take and it may only a partial hearing recovery, I can say that histamine levels and their resulting inflammation can take a good two weeks to resolve even with full effort on your part. Which is why I had suggested people try to follow the program for at least a month to see if it helps them. You may also want to be additionally patient through the summer months as external factors (like I posted last week) such as pollen in the air during "allergy season" could be causing increased histamine levels in people so they may not be experiencing the full benefit of "the program" at this time (though you would likely be a lot worse if you didn't!). Just mentioning this so people don't give up too soon! I am pleased to hear that you are noticing some improvement though, whatever the reason! I hope you continue to get better and better!
Thanks, Ruby Girl, for keeping me in the thread. I know a bit about Histamine. So here is a mini-course. To look at serum Histamine and have any Idea what it means. Different sorces of histamine release have didderent biological half-lives. Most are measures in minutes. Sometimes the peak of the cuve is a few minutes away from the stimulus and others maybe drawn out for hours. Histamine is a messenger chemical. It is used to tell your body there is a problem. Local imflammation any where in or on your body will produce a Histamine responce. I.E. Hit your finger with a hammer. Histamine tell your brain it hurts. Place a sterile tooth pick under your finger nail the brain registers the report as invasion. A virus or bacteria invades your sinus- your nose runs. In a sense histamine is a good thing. It's release tell the brain, there is a problem and sometimes where. In the context of an infectious process it is used to direct IgM and IgG to quickly modifiy their structure to be able target suseceptable invaders. IgE is different in that It's trigger is the enviroonment. It's design trigger can be fungus ( fungus and humans share much the same DNA.). IgE does and will trigger Histamine release. So to limit this diatribe, here is what I suggest. Limit IgE levels. How, try this. There is a fatty acid (docosahexaenoic) DHA, That restricts the expression of IgE. You may have recognized that fatty acid. Fish oil-krill oil. But don't get to excited. Fish oil come from the neverland of unpure. and Krill oli has a dichotomy. It contains 2 major fatty acids. Docosahexaenoic acid (DHA) and Eicosapentaedoic acid EPA. These two fatty acids are complentary. DHA will decrease the effect of IgE while EPA will enhanse it"s effect. An experiment I have not yet performed. What if we reduced the effect of IgE by using purified DHA.
Outside of some effects on Herpes, I don't see an advantage to L-lysine. And in that case I would suggest the fatty acid Lauric acid. Found in cocconut and palm oil. I have also found that multivitamins are not effect supplements. Best to target the problem, then take what you need. Taking a handfull of supplements can inhibit absortion or even change the chemical characteristics. I.E.: taking fatty acids with a fiber meal. Fatty acids stick to fiber, taking calcium, calcium binds to everthing. Alway take with vitamin C. Even Tumeric. changes from yellow to red in your gut. Lauric Acid Effects is a medium-chain saturated fatty acid found in coconut oil and other plant-based oils, and it has various effects on the body. It is known for its antibacterial, antiviral, and antifungal properties, which can help combat pathogens such as bacteria, viruses, and fungi. When converted to monolaurin, it acts as a bacteria-killer and has been shown to be effective against a wide range of harmful pathogens. In terms of health benefits, lauric acid has been associated with improving cardiovascular health by increasing high-density lipoprotein (HDL) levels, which are considered good cholesterol. It may also promote ketosis, which is beneficial for individuals on low-carbohydrate and ketogenic diets. Additionally, lauric acid has shown potential in combating cancer by promoting the destruction of cancer cells and preventing cancer growth, particularly in breast and colon cancer cells. However, the effects of lauric acid on cardiovascular health are not entirely clear. While it can increase HDL levels, it also raises low-density lipoprotein (LDL) levels, which are considered bad cholesterol. This can lead to an increase in total cholesterol levels, although the overall effect on the total cholesterol to HDL ratio may be favorable. A 2016 review of coconut oil, which is nearly half lauric acid, found inconclusive results regarding its effects on cardiovascular disease incidence. Lauric acid also has antimicrobial properties that can help in the treatment of acne by reducing the growth of Propionibacterium bacteria, which is a common cause of acne. It has been shown to be more effective than benzoyl peroxide, a common over-the-counter acne treatment, in reducing bacterial growth on the skin. In addition to its antimicrobial effects, lauric acid has been studied for its potential in reducing inflammation and oxidative stress. It has been found to have anti-inflammatory properties and can help in reducing the risk of neuroinflammation and neuronal damage in conditions such as Alzheimer's disease. However, it can also have side effects, including effects on dyslipidemia and cardiovascular diseases, as it can interact with erythrocytes and affect cellular membranes. Overall, while lauric acid has several potential health benefits, its effects can vary, and more research is needed to fully understand its impact on human health. AI-generated answer. Please verify critical facts. livestrong.com 7 Benefits of Lauric Acid for Your Body | Livestrong.com draxe.com Lauric Acid Benefits: Fight Acne, Infections & More - Dr. Axe pmc.ncbi.nlm.nih.gov Biomedical Applications of Lauric Acid: A Narrative Review - PMC en.wikipedia.org Lauric acid - Wikipedia pmc.ncbi.nlm.nih.gov Lauric Acid, a Dietary Saturated Medium-Chain Fatty Acid, Elicits Calcium-Dependent Eryptosis - PMC chemicalbook.com Applicaton and benefits of Lauric acid_Chemicalbook bebeautiful.in What is Lauric Acid and How Does It Benefit Your Skin skinkraft.com Lauric Acid: Nature’s Gift for Your Skin Care sciencedirect.com Lauric Acid - an overview | ScienceDirect Topics healthline.com Effects of Coconut Oil on Your Health healthline.com Lauric Acid: Research, Psoriasis
Oh, okay! Thanks. I liked the multivitamin because I read it in your list of recommendations on the website.
Not my web site. It's down for update. I am the guy that has a research lab in his house. Though soon my grant from Tennessee may chang that. Larry
Hi All, I'm new to this forum, and I find this thread particularly interesting. I started experiencing symptoms in February, and after seeing several doctors they now agree that I am a suspect Meniere patient. Suspect because, as it turns out, there is now certain way to define this condition. Anyway, now I have two path in front of me. An old school doctors has put me on glycerol (50% diluted), saying that this acts as osmotic recalling the fluids in excess, including the ones from the ears. Second stream is a new school doctor, who says that glycerol is from the 70s and now the therapy is based on a food called SPC flakes, which needs to be taken 1gm/kg/day. After three months it should start giving benefits. Needless to say, they are extremely expensive (25€/450gm/ but of course should they work I don't care). I have seen that both ideas are known in these forums even though the threads I found were not much populated, so difficult to understand the effectiveness. In the meanwhile, reading around, I found an interesting detailed websites talking about histamine effects on Meniere's patients. It's in Italian but maybe you can have it translated, I think it.goes quit technical into this matter. Vertigine ed Istamina I haven't tried yet this kind of dietary, but it's on list and I found this thread very interesting indeed, as it points in the same direction. After months of confusion my approach is now to try the different approaches one by one, to avoid mixing the effects. Question for ruby girl: have you continued you saltless diet or not?
Hello Andrew! Welcome to our little community! To answer your question about the salt: No, I do not activly try to restrict salt. By this I mean that many things that are high salt are high histamine so I avoid those anyway (the aged cheeses, the processed meats, etc.). so it just is naturally lower in salt when you do so. And if I'm cooking where i am adding salt, I will often add an equivalent amount of salt substitute which is potassium chloride usually. Then I am taking in a an equal amount/balace of sodium and potassium which balance each other out in the body. As I say in my document, I am not so sure that all the "evils of salt" are just about the sodium but rather that most people's diets are woefully deficient in potassium that is necessary to buffer the sodium. Sodium is essential to the body too and in fact because I have low blood pressure, restricting my sodium would actually be very harmful to me. But I'm quite happy to shake some salt on my potatoes or my steak because it's just too miserable a life without it to be quite honest. So bottom line is no. No active salt restriction.
Thanks for your reply. Sorry for the stupid question, is there any connection between this treatment with low histamine and the usage of betahistine? I understand betahistine acts in various ways, one of these is blocking one histamine receptor.
Hello Andrew! I am not a pharmacist but from what I can tell betahistine is a "histamine analog" which means it looks like histamine and can fit into the histamine receptors. However it is not exactly histamine so doesn't stimulate cells at 100% when it does "lock in". Basically it's an imposter. This means that when there is too much histamine around, it basically will "block a parking spot" for the real histamine and therefore has an overall antihistamine effect. Yes, for some receptors it will stimulate them a little bit but very little and not the full 100% and for other types of histmine receptors it does the job to lock onto the receptor but really just blocks it from the real thing. If you do a Google search it says "Betahistine is an analog of histamine with weak agonist properties at histamine H1 receptors and more potent anatgonistic effects at histamine H3 receptors." Bottom line: betahistine for all intents and purposes seems to be an overall antihistamine.
Thanks for sharing this. Yes histamine is a factor in autoimmune disease. It is a signaling agent. But not the cause of the disease. In order to control any of the diseases one must block the causitive agent or stop the inflammatory process. In the case of meniere's use of fatty acids is bothe safe and effect. Also the use of natural blocking agent to IgE ( I am now studing the effect of purified DHA orally as step one. Step 2 will be transdermally ). Antihistamines don't fix the cause. I'll let you know how I make out. While I am at it, I havea question. Is the a time, by the clock that you are without symptoms a a time you sense them starting. I am trying to follow cortisol and acth levels with respect to allergen response. Larry
I recently had an medical experience which might shed some light on leaky gut disease. I cured a kitten of feline Parvo virus. In Parvo the inner most layer of intestine sluffs off. You can't get anymore leaky. I will try to make this short. When the inner portion of the intestine is either missing or none functional there is a reason. Without a functional intestine absorbtion relies on tisse transport. In many cases I.E. celiac disease and probably leaky gut the micrville lilli lay down. Like trees after a hurricane. The is a biochemical found inwheat germ brown rice and sorghum that triggers the micro villi to stand up. To that end a help for leaky gut could be the following. Flaxseed oil (linolaic acid. Antiviral and anti-inflammatory) Chicken soup ( don't laugh. Must be home made broth. Resoson for home made. Don't know what is in store bought. Also is probably cooked longer. The cooking breaks down proteins to small peptide and amino acids which a easily absorbed without microvilli. I f the chicken is boiled with the skin on the broth will be hight in Zinc. In the case of the kitten the to the broth was added 20% sorghum syrup. This contains not on only Spermidine to help the microvilli but almany small molecules including glucose an sucrose to support immune response. Nessary for the kitten. hope this helps. Larry
Hi Rubygirl, allow me to ask few more questions. I tried eliminating histamine from my diet. It's extremely difficult but for the first time in 3 months I skipped my weekly vertigo attack. I have a diary of my simpthoms since June, and I notice that every 5-7 days I have a vertigo attack that forces me to bed, from 2 to 12 hours. Yesterday,after 14 good days, started feeling bad, pressure on my ears, let's see if it will get worse. It could be a coincidence of course but one must experiments a bit with MD. I am then trying to think what I have been eating and I am wondering how long I should go back. The thing is, in my understanding there is an accumulation of histamine in the body. So maybe I had a little at lunch (I had to cous cous with vegetables at the canteen yesterday because I had not prepared my lunch), a little more in the evening and the suddenly I have the symptoms . How long does it take for food histamine for being processed? Then I wanted to ask about yiest. Have you removed it completely? I haven't removed bread from my diet for example, maybe that a mistake. Finally I was reading back your posts and I found this about DAO: "and it's only half the battle because then there is histamine that is released INSIDE your body that the DAO doesn't access. That's where the other supplements come in to bypass or assist the biochemical processes" Which other supplements are you using to eliminate histamine? Thanks for your help.