Acyclovir side affects

Discussion in 'Your Living Room' started by Lindy56, Aug 31, 2014.

  1. Lindy56

    Lindy56 New Member

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    May 13, 2014
    I had started taking 400 mg a day and hadn't noticed anything like a side affect except some tinnitus. Today I decided all is good and took 2 pills. After the second dose I have a feeling of something like a band around my head. My face has turned red like a sunburn. I have a redishness anyway like roscea but this is like a major flush. My skin feels tight no hives or anything like that but kind of itchy. I had this same kind of reaction to Macrodentin. And kind of like how penicillin but actually got hives. . I don't know if I should continue taking it and see if it goes away. I don't want a full blown allergic problem like my throat closing up. I fell like it's giving me TMJ too. Now I am feeling a little nervous. It's a very uncomfortable feeling like my face is burning like a chemical burn. I so wanted to be able to take antivirals hoping it would give me a better quality of life now I just don't know.
     
  2. June-

    June- Well-Known Member

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    May 12, 2014
    That is nit a 'normal' side effect with acyclovir if that is what you are asking. I think you should talk to your dr about it. Is there anything else you are taking or possibly ate, that could be responsible. If it were me i would not keep taking it til i figured out what is going on.
     
  3. June-

    June- Well-Known Member

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    You arent taking niacin or anything like that that would cause a flush are you?
     
  4. Lindy56

    Lindy56 New Member

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    No not taking niacin but that is how it feels took that years ago one time. But it went away quickly and no left over problem. My face still feels what I call buzzy and my skin sensitive especially on my arms. Will call the doctor tomorrow and ask him what he thinks. I would have thought this would happen with one dose if its an allergic reaction.
     
  5. Vicki

    Vicki Guest

    take some benedryl and tell your doctor, I agree this is not a normal side effect, it sounds like an allergic reaction to me too. Also as June said it could be coming from something else you ate and its coincidental with the acyclovir but yes pursue it until you know for sure what caused it.

    How long were you taking the 1 pill a day? Also an allergic reaction can happen at anytime even with things we eat or take or use regularly.
     
  6. Vicki

    Vicki Guest

    my allergist tells me to take 50 mg of Benadryl for an allergic reaction every 4-6 hrs but no more than 300 mg for the day
     
  7. Lindy56

    Lindy56 New Member

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    May 13, 2014
    I had been taking the one 400 mg pill for 5 days. It might be from something else. Haven't done anything unusual though not eaten anything that isn't normal for me. Have to say I am disappointed. I don't have hives or throat closing up on anything like that. Will talk to doctor on Tuesday unless I get worse then of course will go to the hospital. Won't take any more until I find out what he thinks. I hope it's a coincidence.
     
  8. Vicki

    Vicki Guest

    I hope so too. I may be wrong but if you find a good allergist and bring the medication with you he may be able to do some type of allergy test with it. The reason I am saying this one of my allergist asked me to bring in a medication I felt was causing an allergic reaction in me, I asked if he could test for it, he said yes bring in the medication. But my tests came back and showed it was a shellfish allergy so never followed through with the medication.
     
  9. Vicki

    Vicki Guest

    http://www.mayoclinic.org/diseases-conditions/drug-allergy/basics/tests-diagnosis/con-20033346

    A physical examination. In addition to a physical exam, your doctor will have a number of questions. For example, he or she might ask how long after you took the medication you began having symptoms.
    •Blood tests. A blood sample can only be used to detect an allergy to a few drugs, such as certain antibiotics, muscle relaxants and insulin. Skin tests are generally preferred because they're more accurate in detecting drug allergy, but blood tests may be used when someone has had a severe reaction in the past, because skin testing could cause another such reaction.
    •Skin tests. For some drugs, including certain antibiotics, an allergy skin test may be used to determine whether you're allergic. A small amount of the drug is injected into the skin of your forearm or back. If you're allergic to the drug being tested, you develop a red, raised bump or other reaction.
    Drug provocation tests. During drug provocation testing, gradually increasing doses of the offending drug are given. The drug can be given in different ways for the test, including orally or under the skin. A reaction indicates a possible allergy or sensitivity to the drug. If reactions to the drug are mild or there's no evidence of an allergic reaction, the drug may be a safe treatment choice. This test is usually used only when an alternative drug won't work as well or isn't an option. It may also be used when skin and blood tests aren't conclusive. Risks include a severe reaction and possibly anaphylaxis. Generally, only specialized allergy centers perform provocation tests for drug allergy.

    Drug allergy treatment generally involves stopping the medication. You may also need medications to ease symptoms or, in the case of a serious reaction, emergency care.
    •Minor reactions such as rashes or hives may improve with an over-the-counter antihistamine such as diphenhydramine (Benadryl, others). Call your doctor before using over-the-counter medications to make sure you're getting the treatment you need.
    •Serious reactions may require treatment with oral or injected corticosteroids at the hospital. Seek emergency treatment if you have severe rashes or hives, swelling, shortness of breath, dizziness, or other signs or symptoms of a severe reaction.
    •Anaphylaxis is an emergency requiring an immediate epinephrine injection and hospital care to maintain blood pressure and support breathing. If you've already had a serious allergic drug reaction, ask your doctor whether you need to carry an epinephrine injection (EpiPen, EpiPen Jr, Twinject).

    Desensitization

    In some cases, sensitivity to a drug can be reduced by starting with a tiny dose and gradually increasing it over time. This is done with medical supervision at a doctor's office, hospital or allergy clinic. In general, this is done only when you're allergic to a drug and a satisfactory alternative isn't available.
     
  10. Vicki

    Vicki Guest

    I found this, not sure it applies to you but I would stop the acyclovir just in case.

    http://fooddrugallergy.ucla.edu/body.cfm?id=38

    I had a burn reaction to antibiotics. Can I take another antibiotic safely?
    Yes, but only after an extensive review of the medication that caused the problem.. Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe skin diseases that can be triggered by adverse drug reactions. These conditions lead to unusual rashes that can resemble very severe burns. The medication that caused the problem and all structurally related drugs must be avoided forever. There is a very high risk the reaction will occur again if the patient receives the same or related medication.
     
  11. Lindy56

    Lindy56 New Member

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    Well Vicki that's interesting about the burn from medication. I thought I was loosing my mind or something. I don't know why I always doubt myself. The clinic I use to go to does penicillin allergy testing. I can't go there now because they are no longer on my insurance. Will check out who is in network if they can test this kind of thing. I went to some website of people with herpes taking medication and some did report a skin sensitivity but to sunlight and some said gave them a fever. Of course not going to be taking this medication for now. Not unless something else happens like all the sudden same burning and haven't been taking it for a while. But it is what it is. I am disappointed because I really wanted to get up to a high dosage and see if I had a drastic improvement. I was feeling like the brain fog was a better. But didn't want to post about it until I took it for a while and made sure it wasn't l a placebo thing going on or jinx myself.
     
  12. Vicki

    Vicki Guest

    if you felt the acyclovir was helping maybe eventually try lysine..since there is a very high risk the reaction will occur again from the same or related medication.

    But I wouldn't try anything now until you speak to your doctor and allergist.
     
  13. Lindy56

    Lindy56 New Member

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    May 13, 2014
    I looked up that disease listed there that causes the burning skin from medications. It gives a list of meds that can cause the disease to happen. Penicillin as well as sulfa drugs both which gave me the same kind of burning sensation. Penicillin though had a rash and the sulfa drug affected my vision along with the burning. So glad I didn't just pop a high dose of the acyclovir strange though I got non of it on a lower dose. It also states that herpes can cause the disease Stevens-Johnson syndrome. I don't have anything like the pictures are showing. I would like to know if this is something that could happen in a more severe way. I don't really know what to think I am baffled. Geesh always something.
     
  14. Vicki

    Vicki Guest

    maybe there are test to see if you have that syndrome, take a picture of your face so you can show your dr when you see him in case it fades by that time.
     
  15. Vicki

    Vicki Guest

    best thing to do while waiting to see your dr is not to take the medication because I read it is treated in ICU, and you don't want it to happen again or more severely, sounds like a rough disease
     
  16. Lindy56

    Lindy56 New Member

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    May 13, 2014
    I read a lot more about it. Nothing to mess with very bad thing to have happen. I am going to make sure I get some answers. thanks for your help
     

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