read a study on high dosages of serc; interesting anyone out there done this with any success? I used serc for several yrs as usual with me I had thought i'd found the magic bullet but it slowly stopped helping was taking 48 mg a day thanks! I had success with a/v's for several months but it has crapped out as well I pop acyclovir 400mg every 2 hrs throughout the day and have for a while but it isn't helping feel like a have a 40lb beatle deep in my left ear
Sorry to hear your not getting the relief you were getting March, April and May are very rough month for MM. Hopefully when the allergy season passes you will start getting more improvements again. I never took Serc, sorry but I too read that study on Serc and I also read some posts from people on other sites who take serc where some it gave them good amount of relief and others it didn't. Seems with every treatment pertaining to MM it helps some but not others which I guess that tells us MM is caused by a variety of things. Have you looked into the anti fungals and probiotics yet? or high doses of Vitamin C? I hope you start feeling better very quickly!
‘Large-dosage’ SERC (Betahistine) has been a blessing for me. More here ...... http://menieres.org/talk/index.php?topic=28.0 I believe that 48mg/day is far too small a dosage, at least, for me. I have been doing 224mg/day for a few months now. My Meniere’s may, or may not, be in a natural state of remission, however, it is undeniable that, after 15 years of fluctuating noise levels (Tinnitus), ‘something’ has brought the noise level down to ‘barely audible’ and my hearing has returned to 80-85% of my normal (although a semi-tone lower). This situation seems to have stabilized and I am presently extremely grateful for “large-dosage” Betahistine.
thanks for the quick reply has it helped with your fullness, balance, etc? how long did it take to notice any difference? I started taking 144 mg yesterday should I go with the higher dosage you are on?
hey Vicki you are such a sweetheart can you tell me in a few words how the anti fungal and probiotics work? thanks
‘Glad to be of assistance, deadeye. As I am not an ENT specialist, I am not equipped to answer your question about your regimen. All I can do is tell my own story and hope that someone, perhaps you, may benefit from it. I have had no vertigo attacks and very little, to no, fullness since I hit, and have maintained, my present SERC dosage. I started at 8mg/3x daily, then to 16mg/3x daily and increased the dosage until I hit 224mg/day (4 tabs/64mg/3x a day and 2 tabs/32mg at bedtime). I was prepared to go as high as necessary until I felt “well”. The highest dosage used in the German test group was 480mg/day. “... high dosages of betahistine dihydrochloride between 288 and 480mg/day seem to be effective in patients who do not sufficiently respond to lower dosages. Moreover, such dosages are well tolerated”. -Department of Neurology, Klinikum Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany. I check into this board, almost daily, so I can try to help however I can. Good luck, deadeye.
Thank you deadeye well it will help with MM if your MM is caused or exacerbated by a systemic fungal infection. Papajoe had good results with it. There was a study I posted on old forums basically saying of other treatments fail to look into a fungal infection as a possible cause. I am on way out when I come back I will post papajoes links and the link to that study.
Hi Deadeye, this is papajoe's pdf file on MM being caused by a systemic fungal infection http://www.papadisc.com/MM_Nystatin.pdf and here is the study http://www.ncbi.nlm.nih.gov/pubmed/24642338
thanks Vicki do you know what the dosages were? i'm ready to give I a try thanks again papa are you out there?
sorry deadeye I don't know the dosage papajoe took and it looks like he didn't register for the new forums
The article under discussion dates back to 2007. “Super-pill may end misery of being fat” 12:01AM GMT 19 Feb 2007 Scientists have stumbled upon a "super-pill" that helps people lose weight at a staggering rate – and could save the NHS millions in risky obesity surgery. The drug, Betahistine, has been safely used to treat vertigo for years, so could be fast-tracked for approval and available by 2009. http://www.telegraph.co.uk/news/uknews/1543094/Super-pill-may-end-misery-of-being-fat.html I’m going to call BS on this “claim”. By now, I should have lost about 40lbs. I haven’t lost any. Go figure ...
I was on betahistine for over two years and didn't lose any weight. On the high dosage issue I told my specialist that when I was having vertigo episodes I took extra tablets over and above the 3 x 16mg per day. He said that taking extra wasn't going to benefit me and instead he prescribed buccastem ( like ativan or valium) to stop a vertigo attack in its tracks or stop it even happening. The buccastem was a life saver for me.
am trying the high dose betahistine anyone know where the cheapest product is? i order it from canada pharmacy doing the high dosage is pretty expensive! thanks
Sorry to hear it’s expensive for you, deadeye. In Canada, I get 270 tabs of Betahistine (16mg) for about $23. British Columbia PharmaCare pays the other 60% of the cost. I hope things change for you soon as, to my knowledge, it is very inexpensive to produce.
this may be helpful if you need more http://hmcompounding.blogspot.com/2011/03/betahistine-use-in-us-interesting-facts.html Betahistine use in the US- interesting facts Betahistine has an interesting history in relation to the FDA, the latest standing being that it is considered an inert chemical, which means that FDA considered Betahistine as being an ineffective drug and removed it from the US market. Yet, based on statistics, 94% of the ENT doctors in Europe/UK prescribe it for their patients with Meniere ’s Syndrome. The good news is that in the US one can get Betahistine by prescription from a compounding pharmacy. More good news is that compared to other FDA approved drugs recommended for the same purpose, Betahistine has the mildest side effects. Understanding of the intricate pharmacology and mechanism of action of the medicine is controversial in scientists’ views. For more detailed information on this medication and its history you may want to check Dr. Timothy C Hain, MD’s compilation in the link bellow: http://www.dizziness-and-balance.com/treatment/drug/serc.html Betahistine is commercially available in many other countries under the name of SERC or BETASERC and bellow is a copy of the package insert for it: http://www.menieres.org/martin.htm#package More up-to-date info from Wikipedia: http://en.wikipedia.org/wiki/Betahistine As every individual is unique, so is the treatment option. Therefore only you and your doctor will decide if this medication will work for you and what will be the most appropriate strength for you. Nurten Rasid, M.D. Clinical Compounding Specialist HM Compounding http://www.hmcompound.com/