Antiviral preference?

EAOfficial · Jan 17, 2024

Mindosa said: ↑

Here is the producers website of these herbal antiviral products:
Lilac Corp: Official Website

Not much info in it. But I found in one study more info about what's inside of these bottles and how they act against the viruses.

Gene-Eden-VIR/Novirin ingredients:

Quercetin

Quercetin is a flavonol with a variety of biological effects, including antioxidant, anti-inflammatory, and antiviral. It has anti-infective and anti-replicative effects on a number of viruses, including RNA viruses. Studies showed that micromolar doses of quercetin can inhibit betacoronavirus infectious activities in vitro. One study reported that quercetin blocked pseudotype SARS-CoV entry into host cells (EC50 = 83.2 μM). Two other studies observed that quercetin specifically inhibited the 2 SARS-CoV proteases, PLpro (IC50 = 8.6 μM21) and 3CLpro (IC50 = 52.7 μM,21 73 μM22), and the Middle Eastern Respiratory Syndrome protease 3CLpro (IC50 = 34.8 μM21). In addition, quercetin’s anti-inflammatory properties may have beneficial effects in respiratory viral infections, including CoV. Studies suggested that quercetin can modulate the cytokine release pattern associated with hyperinflammation and cytokine storm, while upregulating the proliferation of regulatory T helper cells.

Green Tea

Green tea is made of leaves from the plant Camellia sinensis in a process that allows the preservation of certain flavonols commonly known as catechins. Several papers suggested that catechins have broad antiviral effects against many viruses. With regard to beta coronaviruses, one of the main catechins in green tea is epigallocatechin gallate (EGCG). This catechin was found to induce mild inhibitory effects on SARS-CoV 3CLpro (IC50 = 73 μM) in vitro.

Cinnamon

Cinnamon extract is most commonly derived from the species Cinnamomum cassia. Studies demonstrated that the plant has inhibitory effects on RNA viral infections in vitro. Zhuang et al also showed that a cinnamon extract inhibited an infection with the wild type SARS-CoV in vitro (IC50 = 43 μM). The proposed possible mechanism was blocking cell entry via endocytosis.

Licorice

Licorice extract, derived from the root of Glycyrrhiza glabra, has broad antiviral and immunostimulating effects. In vitro and human studies showed that licorice stimulates the proliferation and activation of the human lymphocytes CD4+, CD8+, B cells, and NK cells. Reports from CoV patients indicate the involvement of this type of immune cells prior to the resolution of the disease, while overaccumulation of innate immunity cells, such as macrophages and neutrophils, at the site of infection, was associated with severe cases and death. Thus, licorice may promote early adaptive immunity-mediated clearance of the virus and prevent hyperinflammation. In addition, studies demonstrated a direct weak anti-infective activity of licorice’s main active ingredient, glycyrrhizin, on SARS-CoV in vitro.

Selenium

Selenium is a trace element involved in redox regulation. Its antioxidative effect is exerted through the incorporation as selenocysteine into a group of proteins called selenoproteins. Selenium deficiency increases the levels of reactive oxygen species and oxidative stress, which impairs the response of the immune system to viruses and increases the rate of mutation of RNA viruses. This impaired response may be manifested in several forms: decreased immune cells function, as a result of oxidative damage; decreased cell-mediated immunity; more severe and persistent inflammation of the lungs, as seen in influenza A virus (IAV) infection; and an imbalance in the proliferation of different T cell types, including T helper cells (Th1/Th2) ratio. The increase in viral rate of mutation coupled with the decrease in the immune response to the viral infection may increase virulence, as it increases the population size of quasispecies, and, as a result, gives rise to new more virulent strains. These new strains can become dominant and increase the pathogenicity of the infection. Harthill suggested that this mechanism, which has been observed with other RNA viruses in selenium-deficient mice models, also occurred in the SARS-CoV outbreak in 2002. It is interesting that the outbreak started in areas of low selenium soil in China, such as Wuhan city. It should be noted that excess selenium is also detrimental to health. Studies showed that supranutritional supplementation of selenium caused an imbalance in the proliferation profile of T cell types, and impaired immune response. Finally, studies showed that adequate levels of selenium supplementation to selenium-deficient patients increased the immune response to viral infections, and decreased the virulence of several viruses, in some cases to the point of complete prevention of the disease.
SAGE Journals: Your gateway to world-class research journals

There are a lot of references in this link above about those ingredients effectiveness against viruses.
Maybe it is no side effects solution against viruses together with the lysine?
Click to expand...

Licorice will NOT help you fight any virus or bacteria, and will only hinder. Licorice's main mechanism of action is to significantly increase your body's cortisol, which reduces inflammation, makes the body hold onto water and sodium and lose potassium, AND LOWERS THE IMNUNE SYSTEM

EAOfficial · Jun 4, 2024

IvanA said: ↑

I found studies months ago that ordered efficacy in this order:
1- Valtrex
2- Generic Valacyclovir *
3- Famcyclovir
4- Acyclovir.

* Several users reported years ago that when the pharmacy gave them valaciclovir from the Mylan laboratory they experienced relapses so that brand is not recommended here. But you say that it has worked for you, perhaps they have changed their formula. In any case, switching to another laboratory should not be bad for you.
Click to expand...

What are these studies?
Famvir hasn't been working for me I think, but valacylovir makes me crazy nervous, like eating a salty pretzel and coffee at the same time. I've always been prone to nervousness with salty/carb-rich foods

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