I am newly diagnosed (October), although I think I had symptoms for a year and half prior to that. So far, it has been manageable, but I realize it’s still early. Only a few vertigo attacks, which were mild-moderate and mostly occurred upon waking in the morning. As a lifelong music lover and hobbyist musician, it’s the hearing changes/tinnitus that have been most distressing. I’m symptom-free now and have been since I was diagnosed and put on sodium restriction and a diuretic. An audiogram in November found no hearing loss in my affected ear and ECoG was inconclusive. When I was diagnosed, my ENT heavily pitched the idea of immediately beginning intratympanic steroid injections as an early intervention to forestall hearing loss. Scared of losing my hearing, I was all for it. But now I’m thinking I should wait a bit to see how the disease progresses. Anyhoo… on to my question…does anyone here take N-Acetyl Cysteine (NAC), and if so, what has been your experience? There doesn’t seem to be much on the internet related to Meniere’s. However, there has been some research on NAC and prevention of hearing loss from noise exposure and ototoxic drugs (cisplatin, in particular). NAC is an antioxidant whose current main medical use is as the standard treatment for acetaminophen overdose. It’s a precursor to the powerful free-radical scavenger glutathione as well as to the neurotransmitter glutamate. The latter has caused it to be recommended by some holistic psychiatrists as a complementary, non-pharmacologic therapy for anxiety and OCD. NAC is generally safe to take and has been part of my supplement regimen for a few years (600 mg.). Now I’m thinking about increasing my dose the next time I have tinnitus related to Meniere’s. I have not discussed this yet with my ENT, but I’m wondering if NAC would have a protective effective on cochlear hair cells.