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you may want to read this...this is where its all headed!! Immune therapy

Discussion in 'Your Living Room' started by Bulldogs, Jun 10, 2016.

  1. Bulldogs

    Bulldogs Well-Known Member

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    Hope for multiple sclerosis cure as 23 seriously ill patients recover after 'breakthrough' stem cell treatment
    Jennifer Molson skis after recovering from Multiple Sclerosis
    Jennifer Molson skis after recovering from Multiple Sclerosis CREDIT: THE OTTAWA HOSPITAL
    Sarah Knapton, science editor
    10 JUNE 2016 • 7:06AM
    Multiple sclerosis patients who were severely disabled are walking, working and even downhill skiing again following a breakthrough therapy which completely destroys, then rebuilds, the immune system.

    The trial, which is the first in the world to show complete long-term remission from the debilitating disease has been hailed by experts as ‘exciting’ ‘unprecedented,’ and ‘close to curative.’

    Although it is unclear what causes MS it is thought that the immune system attacks the protective coating which surrounds nerve cells in the brain and spinal cord leading to inflammation, pain, disability and in severe cases, early death.

    Can a new immune system halt MS and allow repair?
    The new technique, which is a treatment usually used to fight leukaemia, involves using chemotherapy to entirely eradicate the damaged immune system, before rebooting it with a transfusion of bone marrow cells.

    Out of the 24 patients who were given the treatment at least seven years ago, the majority have seen significant improvements . 70 per cent of patients saw a complete stop to the progression of the disease, while 40 per cent saw a reversal in symptoms such as vision loss, muscle weakness and balance loss.

    Jennifer, she freaked me out one day when she came to the clinic wearing high heels. This was a girl who could barely walk.
    Dr Mark Freedman
    Some participants were able to return to work, school, regain the ability to drive, get married and have children.

    Trial participant Jennifer Molson, who was diagnosed with MS in 1996, and received her stem cell transplant in 2002 said: “Before my transplant I was unable to walk or work and was living in assisted care.

    “Now I am able to walk independently, live in my own home and work full time. I was also able to get married, walk down the aisle with my Dad and dance with my husband.

    “I’ve even gone downhill skiing. Thanks to this research I have been given a second chance at life.”

    Dr Mark Freedman, of the University of Ottawa and Ottawa Hospital, where the trials were carried out, said: “Jennifer, she freaked me out one day when she came to the clinic wearing high heels. This was a girl who could barely walk.”

    MS affects around 100,000 people in Britain. Similar trials have been taking place across the UK and the US but none has shown such long term remission.

    The trial included 24 participants with aggressive, relapsing MS who were followed for up to 13 years after treatment.

    The procedure involves giving a person medication to coax their stem cells to migrate from their bone marrow into their blood.

    These stem cells are then collected from the blood, purified and frozen.

    Then, high doses of chemotherapy drugs are used to eliminate the person’s diseased immune system.

    The frozen stem cells are then frozen and transplanted back into the same person, so that they can give rise to a new immune system that has no memory of the previous pattern of attacking the central nervous system.

    Dr Mark Freedman, Dr Harold Atkins, Jennifer Molson and trial coordinator Marjorie Bowman
    Dr Mark Freedman, Dr Harold Atkins, Jennifer Molson and trial coordinator Marjorie Bowman CREDIT: THE OTTAWA HOSPITAL
    “Our trial is the first to show the complete, long-term suppression of all inflammatory activity in people with MS,” said Dr Harold Atkins, a stem cell transplant physician and scientist at The Ottawa Hospital, and associate professor at the University of Ottawa.

    “A variation of this procedure has been used to treat leukaemia for decades, but its use for auto-immune diseases is relatively new.

    “This is very exciting. However, it is important to note that this therapy can have serious side effects and risks, and would only be appropriate for a small proportion of people with very active MS.”

    During the trial one participant died of liver failure due to the treatment and another required intensive care for liver complications.

    Dr Emma Gray, Head of Clinical Trials at the MS Society, said: “This type of stem cell transplantation is a rapidly evolving area of MS research that holds a lot of promise for people with certain types of MS.

    “This treatment does offer hope, but it’s also an aggressive procedure that comes with substantial risks and requires specialist aftercare. If anyone is considering HSCT we’d recommend they speak to their neurologist.”

    Jennifer Molson kayaking
    Jennifer Molson kayaking CREDIT: THE OTTAWA HOSPITAL
    But experts said the results constituted a breakthrough in the treatment of MS.

    Prof Siddharthan Chandran, MacDonald Professor of Neurology, MRC Centre for Regenerative Medicine, University of Edinburgh, said: “This is an important and carefully conducted proof of concept study that demonstrates that powerful chemotherapy based treatment for a selected subset of MS patients with very aggressive disease is effective in preventing further disabling relapses and, in a proportion, appears to render them effectively disease free.”

    Dr Stephen Minger, stem cell biologist and independent consultant, of SLM Blue Skies innovations Ltd said: “The clinical results are truly impressive, in some cases close to being curative.

    “For a life-long progressive disease like MS with few treatment options this is really exciting data. I would consider it a breakthrough therapy.”

    The research was published in The Lancet.
     
  2. Bulldogs

    Bulldogs Well-Known Member

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    http://www.telegraph.co.uk/science/2016/06/09/multiple-sclerosis-patients-walking-working-and-skiing-after-gro/
     
  3. BumbleBea

    BumbleBea Fallen Angel

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    I was going to ask this today.

    Is Menieres an immune disorder and if so, are their other words to describe the immune disorder and which most fits MM. Even if there are more than one.

    Great info BD!
     
  4. yanksgirl

    yanksgirl Member

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    I also read an article from the UK about a 'trial' treatment study for Meniere's and it concluded that it 'strongly' leaned toward MM being an auto-immune type of condition. I got the email and meant to post it here. Could be from the same website for this study mentioned here.
     
  5. scott tom

    scott tom Active Member

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    How is the antiviral treatment so successful if it's auto immune?
     
  6. June-

    June- Well-Known Member

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    Everything in the body is conencted. A completely healthy immune system would probably fight off a virus on its own. It's not either or, it's all connected. Words like 'immune system' are artifices that help doctors and the rest of us get a handle on understanding but that is all.
     
  7. imback

    imback Member

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    That is the frustrating part June. When they do the blood test that supposedly measures the immune system mine is perfect. I also.wonder if that is why menieres symptoms are so irratic and there is remission, because our immune systems are up and down.
     
  8. June-

    June- Well-Known Member

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    Tests are so limited and they dont know what exactly to test. Go with what works for you. Try to find a doctor who will work with you and dont expect instant results, it is often two steps forward and one back. Wish we had all the answers but no one does yet. Good luck.
     
  9. dolfan

    dolfan Member

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    Good advice June, now how do I deal with a menopausal wife?
     
  10. BumbleBea

    BumbleBea Fallen Angel

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    I knew someone here said that to me!!
    It was you June, lol.
    When I started the Acyclovir and was disgusted because I kept having setbacks and you said" two steps forward, one step back"!!

    Now this will be my new day to day saying as I wait for the Valcyclovir putting me back into remission!

    I'm very confused about the differences between MM being described as caused by a virus.
    I know nothing about immune systems or the disorders.
    Can both be manifested at the same or are they considered to be the same?
    How does MM fall into the immune system?
     
  11. scott tom

    scott tom Active Member

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    Except that nobody's immune system is geared to fight off herpes. It's a tenacious virus that affects virtually everyone who gets it.
     
  12. littlebird

    littlebird New Member

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    I wish everyone would stop talking like we know for sure Menieres is a virus. It's not certain at all. It's just one possibility.
     
  13. scott tom

    scott tom Active Member

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    It may not be 100% certain, but it's by far the most likely explanation. Please provide another theory that explains the 90%+ success rate that Gacek and other medical centers are having with anti-virals that specifically target herpes virus.
     
  14. Bulldogs

    Bulldogs Well-Known Member

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    JOH makes the same claims about his protocol.....it is absolute distortion of the truth and is a nothing more than propaganda.

    Littlebird: trust me 90% of people taking JOH or antivirals for mm are not cured and living completely symptom free.

    It is a narrative that has been pushed and one that after speaking with Dr. Gacek personally (the father in Mass, and the son in Alabama will tell you the same thing).

    Try, them and if they help great, keep taking them, but I agree with you, it gets a little old!!!

    90% cure rate? Pffffft
     
  15. John of Ohio

    John of Ohio Active Member

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    The critic (above) who castigates my claims of significant symptomatic relief (variously in the high 80% range) is making things up. I don't. I derive my claims from the several hundred regimen user responses I've archived. There is no "propaganda" emanating from me on the matter. Why should there be? I gain nothing from regimen users who either gain symptomatic relief or do not. I don't sell anything, and profit no way from anyone's responses.

    "Distortion of the truth?" Just what, per chance, is the evidence for that? Just why should anyone trust this poster on this matter? Is he or she claiming the unsolicited regimen user accounts are fabricated by those who submit them? Why have so many dozens upon dozens of people falsely reported symptomatic relief? What did they gain by such falsification?

    Or, is the poster implying (seems so) that I've fabricated and falsely presented the data? I take great offense at that implication. It is libelous and defamatory. My documented user accounts are evidence. My 140 pages (274 written, user accounts) of regimen successes and failures are the source of the claim.

    --John of Ohio
     
  16. Bulldogs

    Bulldogs Well-Known Member

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    If I told you eating blueberries naked until I puked and then running around the block yelling I love blueberries worked for me am cured me and then a few others had the same result sent via email could I claim eating blueberries Naked until one pukes is the answer? I got 100% cure rate according to my emails but what I or you don't account for is the thousands who tried it and it did not work and they never sent an email!!

    It's like he silent majority that never complain at a restaurant and never come back but the owner thinks everybody loves his good because a few sati it was good...meanwhile in 6 months he is out of business saying I himself......but everybody loved my food, they told me so. Pffft
    The majority actually thought it was awful and never came back not did they tell the owner/manager it was awful.

    Until you understand advanced statistics and linear equations based on on advanced metrics and analytics pertaining to standard of deviations and calculated means, medians and ranges then those emails will get you to believe almost anything.

    But most people never write, email or respond to any product, survey or questionnaire.

    Your a good man JOH but take a deep breath and throw that 90% claim out the window and watch it fall like a led balloon.

    Be good my friend.
    You are a good man a do a lot for mm but it does not pass the smell test at 90%.

    Regards!
     
  17. scott tom

    scott tom Active Member

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    I don't believe for a second that Gacek or his son told anyone that. Post the exact conversation or have him post here to say that. Otherwise, it's just unfounded internet nonsense.
     
  18. Bulldogs

    Bulldogs Well-Known Member

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    If Dr Gacek one in Alabama and one in Mass can promise a 90% cure rate, I will personally pay for the plane ticket and appointment and medicine.... His 2 week protocol.

    But if it fails

    You have to pay me double my cost?

    You have a 90% chance of taking his protocol and never having to deal with mm again. I would take those odds to Vegas any day!!!!

    Any takers....I will sponsor 10 people.

    Better yet my wife is a dr. And I will get her to prescribe the AV's at Dr. Gaceks recommended protocol and if they cure you I will give you 500.00 if not you owe me 1,000.00

    Symptom free and based on advanced blood work and hearing test.
     
  19. moodymom27

    moodymom27 Active Member

    I can't seem to find anyone that accepts my insurance and will also prescribe the antiviral. Even my gp won't do it. I tried really hard with two different doctors and was shot down even giving them the article. That is why I went with gent shots. They helped but it's still not gone. I'm better than I was in the spring but not symptom free. I still get nystagmus and mini spins regularly. But my hearing has improved, go figure? Well, kinda improved. Have to wait and see once this eardrum perforation heals up. I can't afford to go out of network especially since were drowning in medical bills from me and my daughter the past seven months. And I don't have $1000 lol. I'm on my third ENT since December.
     
  20. BumbleBea

    BumbleBea Fallen Angel

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    Can I just have the money?
     

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